Brings Precision AI to Angiography

AngioInsight™ is an investigational software device being designed to improve diagnosis of coronary artery and microvascular disease by using precise AI/ML technology to deliver real time results. Committed to accuracy and efficiency, we aim to give patients answers sooner and reduce the cost of care

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Why Coronary Assessment Needs More Clarity

20.5M+
U.S. adults living with coronary artery disease1
2.2M
U.S. CAD patients undergo angiography each year2
~2M
Clinical diagnostic decisions rely on subjective interpretation3
40%
Of patients with angina have CMD
(up to half are women)4

Why Current Approaches Fall Short

Current coronary assessment methods are primarily designed to evaluate epicardial disease and often rely on visual interpretation. As a result, abnormalities in the microvasculature may go undetected—particularly in patients with persistent symptoms despite non-obstructive findings. This diagnostic gap contributes to variability in interpretation, incomplete explanations for angina, and delayed recognition of disease, disproportionately affecting women.

1

Acquire

Uses standard angiographic video; no changes to standard image acquisition and no user tracing of vessels
2

Analyze

AI models are being developed to evaluate vessel anatomy and flow characteristics
3

Act

Designed to present analysis results for clinician interpretation in the cath lab

CAUTION: The AngioAI+™ platform is an investigational device. Limited by Federal (or United States) law to investigational use.

how it works

AngioAI+ Technology (Features Under Development)

AngioAI+ is an investigational software platform under development, designed to analyze routine angiographic video to support insights into coronary anatomy, flow patterns, and microvascular function.

Advanced AI Architecture

AngioAI+ is being developed using modern AI architectures designed to process complex, high-dimensional imaging data. These approaches go beyond early-generation machine learning techniques by enabling analysis of spatiotemporal patterns present in angiographic video.

Dynamic Video-Based Analysis – Not Static Images

Unlike approaches that rely on static image frames, AngioAI+ is designed to analyze full angiographic video sequences. This allows the platform to evaluate contrast dynamics over time, supporting exploration of physiologic patterns that may not be apparent in single-frame analysis.

Flow-Focused Data Modeling

By evaluating contrast transit across coronary vessels, AngioAI+ is intended to model the coronary circulation as a dynamic system rather than a series of isolated images.

3D Vessel Reconstruction From Standard Angiography

AngioAI+ is being developed to generate three-dimensional representations of coronary vessel geometry from standard angiographic video, without the need for additional hardware.

  1. Tsao CW, et al. Heart Disease and Stroke Statistics—2024 Update. Circulation. 2024.
  2. American Heart Association. “Heart Disease and Stroke Statistics—2021. Circulation 2021 Feb 23;143(8):e254-e743. doi: 10.1161/CIR.0000000000000950. Epub 2021 Jan 27.
  3. PubMed Journal of the American College of Cardiology, 59(9), 857-881. J Am Coll Cardiol 2017 May 2;69(17):2212-2241. doi: 10.1016/j.jacc.2017.02.001. Epub 2017 Mar 10.
  4. Tripathy et al., Eur Heart J Case Rep, 2025